In the last 13 months there have been 544 traffic crashes on the road.
"Remind people we've have some loss of life out here and a lot of property damage we don't want any more," Saginaw County Sheriff Bill Federspiel said.
In less than two weeks, two fatal accidents have happened on Gratiot.
The safest thing drivers can do to prevent accidents is to follow the speed limit, Federspiel said.
"Slow down, go the speed limit. When you see a yellow light don't step on the gas to get through," he said.
The Michigan Department of Transportation is also taking note of the accident prone road.
Next summer MDOT will redesign stretches of the road to make it safer, said Jack Hofweber, MDOT spokesperson.
Under the plan crews will close down dangerous crossovers and construct four new turnarounds.
"Very effective for flow of traffic, making it safer and more efficient," Hofweber said.
In the meantime, Federspiel said his department is keeping a close eye on the road and deputies are on the lookout for anyone speeding through busy intersections.
"Shifting our resources now to Gratiot throughout the entire county to make sure we reduce those fatalities," Federspiel said.
While there have been calls to lower the speed limit on sections of Gratiot, MDOT said it has no plans to do so.
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